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Tuesday, June 09 2015
Posted by: Dr. Dan L. Boen AT 10:19 am   |  Permalink   |  Email
Tuesday, September 23 2014

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GleaningsGleanings

September 23, 2014

1 in 4 Pastors Have Struggled with Mental Illness, Finds LifeWay and Focus on the Family

Family ministry has LifeWay Research examine how well (or not well) churches address mental health.
1 in 4 Pastors Have Struggled with Mental Illness, Finds LifeWay and Focus on the Family

[Updated with Ed Stetzer quotes]

Your pastor is just as likely to experience mental illness as any other American, according to a LifeWay Research survey commissioned by Focus on the Family.

Nearly 1 in 4 pastors (23 percent) acknowledge they have “personally struggled with mental illness,” and 12 percent of those pastors said the illness had been diagnosed, according to the poll (infographics below). One in four U.S. adults experience mental illness in a given year, according to the National Alliance on Mental Illness.

Recent deaths by suicide of high-profile pastors’ children, including Rick Warren’s son Matthew and Joel Hunter's son Isaac, have prompted increased attention to mental illness from pastors’ pulpits and pens. Warren launched “The Gathering on Mental Health and the Church” this past spring. High-profile pastors, including NewSpring Church pastor Perry Noble, have publicly documented their struggles with mental illness.

“Here’s what we know from observation: If you reveal your struggle with mental illness as a pastor, it’s going to limit your opportunities,” Ed Stetzer, executive director of LifeWay Research, told CT. “What happens is pastors who are struggling with mental illness tend not to say it until they are already successful. So Perry Noble, running a church of 30,000 plus, just last year says ‘I have severe depression.’”

“We have to break the stigma that causes people to say that people with mental illness are just of no value,” he added. “These high-profile suicides made it okay to talk about, but I think Christians have been slower than the population at large to recognize what mental illness is, let alone what they should do."

The majority of pastors (66 percent) still rarely or never talk about mental illness in sermons or before large groups, the survey found. About one-fourth of pastors bring up mental illness several times a year, and 7 percent say they tackle it once a month or more.

Image: LifeWay Research

Struggling laypeople wish their churches dealt with the issue more; 59 percent of respondents with a mental illness want their church to talk more openly about it, as do 65 percent of their family members.

“Our research found people who suffer from mental illness often turn to pastors for help,” Stetzer noted in a news release. “But pastors need more guidance and preparation for dealing with mental health crises. They often don’t have a plan to help individuals or families affected by mental illness, and miss opportunities to be the church.”

Other “key disconnects” uncovered by the study:

  • Two-thirds of pastors (68 percent) say their church maintains a list of local mental health resources for church members. But few families (28 percent) are aware those resources exist.
  • Only a quarter of churches (27 percent) have a plan to assist families affected by mental illness, according to pastors. And only 21 percent of family members are aware of a plan in their church.
  • Few churches (14 percent) have a counselor skilled in mental illness on staff, or train leaders how to recognize mental illness (13 percent), according to pastors.

The disconnect isn’t because of a lack of compassion. Most pastors (74 percent) say they aren’t reluctant to get involved with those with acute mental illnesses, and nearly 60 percent have provided counseling to people who were later diagnosed.

Image: LifeWay Research

Instead, pastors can feel overwhelmed at times with how to properly respond to the mental health needs of members of their congregation; 22 percent said they were reluctant to do more because it took “too much time.”

“Pastors are trained for spiritual struggle. They’re not trained for mental illness,” Stetzer told CT. “And so, what they will often do is pass someone off. I don’t think what that 20 percent says is ‘Forget you,’ but ‘I can’t handle this.’”

The silence at church can lead to a reluctance to share, Atlanta-based psychiatrist Michael Lyles told LifeWay. “The vast majority of [my evangelical Christian patients] have not told anybody in their church what they were going through, including their pastors, including small group leaders, everybody,” he said in the release.

In fact, 10 percent of the 200 respondents with mental illness said they have switched churches after a church’s poor response to them, and another 13 percent stopped going altogether or couldn’t find a church.

But more than half of regular churchgoers with mental illness said they stayed where they were, and half also said that their church has been supportive. One way churches can be supportive, Stetzer suggested to CT, is regular meetings between pastoral staff and the person suffering from mental illness, even as the individual continues to receive consistent medical treatment.

“The Bible is filled with people who struggled with suicide, or were majorly depressed or bi-polar,” said Focus on the Family pyschologist Jared Pingleton in the LifeWay release. “David was totally bi-polar. Elijah probably was as well. They are not remembered for those things. They are remembered for their faith.”

Researchers focused on three groups:

They surveyed 1,000 senior Protestant pastors about how their churches approaches mental illness. Researchers then surveyed 355 Protestant Americans diagnosed with an acute mental illness—either moderate or severe depression, bipolar, or schizophrenia. Among them were 200 church-goers.

A third survey polled 207 Protestant family members of people with acute mental illness.

Researchers also conducted in-depth interview with 15 experts on spirituality and mental illness.

LifeWay's full release is copied below.

CT frequently addresses mental health, including how pastors can guard against mental illness, the spiritual side of mental illness, how Facebook can affect your mental health, and how nothing, not even suicide, can separate people from the love of God. CT also covered Saddleback Church senior pastor Rick Warren’s mental health ministry launch after his son Matthew took his own life in 2013.

-----

Mental Illness Remains Taboo Topic for Many Pastors

By Bob Smietana

NASHVILLE, Tenn. – One in four Americans suffers from some kind of mental illness in any given year, according to the National Alliance on Mental Illness. Many look to their church for spiritual guidance in times of distress.But they're unlikely to find much help on Sunday mornings.

Most Protestant senior pastors (66 percent) seldom speak to their congregation about mental illness.

That includes almost half (49 percent) who rarely (39 percent) or never (10 percent), speak about mental illness. About 1in 6 pastors (16 percent) speak about mental illness once a year. And about quarter of pastors (22 percent) are reluctant to help those who suffer from acute mental illness because it takes too much time.

Those are among the findings of a recent study of faith and mental illness by Nashville-based LifeWay Research. The study, co-sponsored by Focus on the Family, was designed to help churches better assist those affected by mental illness.

Researchers looked at three groups for the study.

They surveyed 1,000 senior Protestant pastors about how their churches approaches mental illness. Researchers then surveyed 355 Protestant Americans diagnosed with an acute mental illness—either moderate or severe depression, bipolar, or schizophrenia. Among them were 200 church-goers.

A third survey polled 207 Protestant family members of people with acute mental illness.

Researchers also conducted in-depth interview with 15 experts on spirituality and mental illness.

The study found pastors and churches want to help those who experience mental illness. But those good intentions don’t always lead to action.

"Our research found people who suffer from mental illness often turn to pastors for help," said Ed Stetzer, executive director of LifeWay Research.

"But pastors need more guidance and preparation for dealing with mental health crises. They often don’t have a plan to help individuals or families affected by mental illness, and miss opportunities to be the church."

A summary of findings includes a number of what researchers call ‘key disconnects’ including:

Only a quarter of churches (27 percent) have a plan to assist families affected by mental illness according to pastors.And only 21 percent of family members are aware of a plan in their church. Few churches (14 percent) have a counselor skilled in mental illness on staff, or train leaders how to recognize mental illness (13 percent) according to pastors. Two-thirds of pastors (68 percent) say their church maintains a list of local mental health resources for church members. But few families (28 percent) are aware those resources exist. Family members (65 percent) and those with mental illness (59 percent) want their church to talk openly about mental illness, so the topic will not be a taboo. But 66 percent of pastors speak to their church once a year or less on the subject.

That silence can leave people feeling ashamed about mental illness, said Jared Pingleton, director of counseling services at Focus on the Family. Those with mental illness can feel left out, as if the church doesn’t care. Or worse, they can feel mental illness is a sign of spiritual failure.

"We can talk about diabetes and Aunt Mable’s lumbago in church—those are seen as medical conditions,” he said. “But mental illness--that’s somehow seen as a lack of faith."

Most pastors say they know people who have been diagnosed with mental illness. Nearly 6 in 10 (59 percent) have counseled people who were later diagnosed.

And pastors themselves aren’t immune from mental illness. About a quarter of pastors (23 percent), say they’ve experienced some kind of mental illness, while 12 percent say they received a diagnosis for a mental health condition.

But those pastors are often reluctant to share their struggles, said Chuck Hannaford, a clinical psychologist and president of HeartLife Professional Soul-Care in Germantown, Tennessee. He was one of the experts interviewed for the project.

Hannaford counsels pastors in his practice and said many – if they have a mental illness like depression or anxiety—won’t share that information with the congregation.

He doesn't think pastors should share all the details of their diagnosis. But they could acknowledge they struggle with mental illness.

"You know it’s a shame that we can’t be more open about it,” he told researchers. “But what I’m talking about is just an openness from the pulpit that people struggle with these issues and it’s not an easy answer."

Those with mental illness can also be hesitant to share their diagnosis at church. Michael Lyles, an Atlanta-based psychiatrist, says more than half his patients come from an evangelical Christian background.

"The vast majority of them have not told anybody in their church what they were going through, including their pastors, including small group leaders, everybody," Lyle said.

Stetzer said what appears to be missing in most church responses is "an open forum for discussion and intervention that could help remove the stigma associated with mental illness."

"Churches talk openly about cancer, diabetes, heart attacks and other health conditions – they should do the same for mental illness, in order to reduce the sense of stigma," Stetzer said.

Researchers asked those with mental illness about their experience in church.

A few – (10 percent)—say they’ve changed churches because of how a particular church responded to their mental illness. Another 13 percent ether stopped attending church (8 percent) or could not find a church (5 percent). More than a third, 37 percent, answered, “don’t know,” when asked how their church’s reaction to their illness affected them. Among regular churchgoers with mental illness, about half (52 percent) say they have stayed at the same church. Fifteen percent changed churches, while 8 percent stopped going to church, and 26 percent said, “Don’t know.” Over half, 53 percent, say their church has been supportive. About thirteen percent say their church was not supportive. A third (33 percent) answered, “don’t know” when asked if their church was supportive.

LifeWay Research also asked open-ended questions about how mental illness has affected people’s faith. Those without support from the church said they struggled.

“My faith has gone to pot and I have so little trust in others,” one respondent told researchers.

“I have no help from anyone,” said another respondent.

But others found support when they told their church about their mental illness.

“Several people at my church (including my pastor) have confided that they too suffer from mental illness,” said one respondent. “Reminding me that God will get me through and to take my meds,” said another.

Mental illness, like other chronic conditions, can feel overwhelming at times, said Pingleton. Patients can feel as if their diagnosis defines their life. But that’s not how the Bible sees those with mental illness, he said.

He pointed out that many biblical characters suffered from emotional struggles. And some, were they alive today, would likely be diagnosed with mental illness.

“The Bible is filled with people who struggled with suicide, or were majorly depressed or bi-polar, he said. “David was totally bi-polar. Elijah probably was as well. They are not remembered for those things. They are remembered for their faith.”

LifeWay Research’s study was featured in a two-day radio broadcast from Focus on the Family on September 18 and 19. The study, along with a guide for pastors on how to assist those with mental illness and other downloadable resources, are posted at ThrivingPastor.com/MentalHealth.

LifeWay Research also looked at how churches view the use of medication to treat mental illness, about mental and spiritual formation, among other topics. Those findings will be released later this fall.

Methodology:
LifeWay Research conducted 1,000 telephone surveys of Protestant pastors May 7-31, 2014. Responses were weighted to reflect the size and geographic distribution of Protestant churches. The sample provides 95% confidence that the sampling error does not exceed +3.1%. Margins of error are higher in sub-groups.

LifeWay Research conducted 355 online surveys July 4-24, 2014among Protestant adults who suffer from moderate depression, severe depression, bipolar, or schizophrenia. The completed sample includes 200 who have attended worship services at a Christian church once a month or more as an adult.

LifeWay Research conducted 207 online surveys July 4-20, 2014 among Protestant adults who attend religious services at a Christian church on religious holidays or more often and have immediate family members in their household suffering from moderate depression, severe depression, bipolar, or schizophrenia.

Posted by: Dr. Dan L. Boen AT 01:18 pm   |  Permalink   |  Email
Wednesday, September 17 2014
MedlinePlus Logo

Blood Test Spots Adult Depression: Study

It's as accurate as current methods, but can also confirm recovery, researchers contend
URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_148403.html (*this news item will not be available after 12/15/2014)

 
Tuesday, September 16, 2014 HealthDay Logo
HealthDay news image

TUESDAY, Sept. 16, 2014 (HealthDay News) -- A new blood test is the first objective scientific way to diagnose major depression in adults, a new study claims.

The test measures the levels of nine genetic indicators (known as "RNA markers") in the blood. The blood test could also determine who will respond to cognitive behavioral therapy, one of the most common and effective treatments for depression, and could show whether the therapy worked, Northwestern University researchers report.

Depression affects nearly 7 percent of U.S. adults each year, but the delay between the start of symptoms and diagnosis can range from two months to 40 months, the study authors pointed out.

"The longer this delay is, the harder it is on the patient, their family and environment," said lead researcher Eva Redei, a professor in psychiatry and behavioral sciences and physiology at Northwestern's Feinberg School of Medicine in Chicago.

"Additionally, if a patient is not able or willing to communicate with the doctor, the diagnosis is difficult to make," she said. "If the blood test is positive, that would alert the doctor."

The study, published online Sept. 16 in Translational Psychiatry, with funding from the U.S. National Institute of Mental Health and the Davee Foundation, established the test's effectiveness with 32 adults who were diagnosed as depressed and 32 nondepressed adults. All of the study participants were between 21 and 79 years old.

The test works by measuring the blood concentration of the RNA markers. A cell's RNA molecules are what interpret its genetic code and then carry out those instructions from DNA. After blood is drawn, the RNA is isolated, measured and compared to RNA levels expected in a nondepressed person's blood.

Redei's team administered the blood test to all 64 participants in the study. Then, after 18 weeks of face-to-face or phone therapy for those participants with depression, the test was repeated on 22 of them.

Among the depressed participants who recovered with therapy, the researchers identified differences in their RNA markers before and after the therapy. Meanwhile, the concentration of RNA markers of patients who remained depressed still differed from the original results of the nondepressed patients.

Three of the RNA markers in the adults who recovered remained a little different from those who were never depressed, indicating the possibility that these markers might show a susceptibility to depression, the authors noted.

Additionally, if the levels of five specific RNA markers line up together, that suggests that the patient will probably respond well to cognitive behavioral therapy, Redei said. "This is the first time that we can predict a response to psychotherapy," she added.

The blood test's accuracy in diagnosing depression is similar to those of standard psychiatric diagnostic interviews, which are about 72 percent to 80 percent effective, she said.

The findings were welcomed by one mental health expert.

"The mental health profession has, for decades, been seeking an objective measure for detecting major psychiatric disorders," said Dr. Glen Elliott, chief psychiatrist and medical director of the Children's Health Council in Palo Alto, Calif. "That the authors seem to have found a measure in such a small sample that appears to be sensitive to a specific treatment -- and a psychological intervention at that -- is striking if it holds up."

However, he noted that the small number of study participants means that it is too soon to know the significance of the findings or what the drawbacks of the test could be.

"It is too early to tell how a test of this nature -- even if proven reliable, sensitive and specific -- would be best used in a clinical setting," Elliott said. But he said the findings fit into the larger effort to personalize diagnoses and treatments based on biological data from patients.

"It is an exciting possibility that could, in theory, greatly enhance treatment efficacy and efficiency," Elliott said. "However, especially in psychiatry, we are still a long way from having a reliable product that will accomplish those goals."

The new blood test is not yet available because additional studies with large groups of people must first confirm its accuracy and effectiveness before it can be considered by the U.S. Food and Drug Administration for approval.

Depending on funding, that could take several years, Redei said. If approved, the blood test's costs would be "in the range of other specialty tests," she said.

SOURCES: Eva Redei, Ph.D., David Lawrence Stein Research Professor of Psychiatric Diseases Affecting Children and Adolescents, Asher Center for the Study and Treatment of Depressive Disorders, Northwestern University Feinberg School of Medicine, Chicago; Glen Elliott, Ph.D., M.D., chief psychiatrist and medical director, the Children's Health Council, emeritus professor of clinical psychiatry, University of California, San Francisco, and professor of clinical psychiatry, Stanford School of Medicine, Calif.; Sept. 16, 2014, Translational Psychiatry, online

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Page last updated on 17 September 2014
Posted by: Dr. Dan L. Boen AT 12:20 pm   |  Permalink   |  Email
Monday, September 15 2014
 
 
 
I Didn't Marry My Best Friend
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At many weddings these days, whether on picturesque hillsides or at funky warehouses or in swanky ballrooms, newly minted husbands and wives proudly declare to friends and family, “I married my best friend.”

If you attended a wedding this summer, you likely heard the phrase, now so standard in romantic rhetoric that we forget it’s not part of the traditional ceremony. “I married my best friend” appears in vows, program dedications, toasts, and other aww-inducing moments (not to mention the cards, frames, cufflinks, wine glasses, and other Etsy-inspired wares that attend modern weddings).

The sentiment, repeated in Facebook posts on anniversaries, is shorthand for the special relationship with someone we are comfortable with, who listens, loves, and encourages. From secular folks to Christians who firmly believe that God sent them the one, nearly all the married people I know are “so blessed” (or “lucky”) to get to spend their lives wedded to their best friends.

Even if couples don’t announce that they’re marrying their best friend, many newlyweds live out this philosophy, dropping out of the friend-making game once they have a ring on their finger. Sociologists find that these days, we typically form our most meaningful friendships prior to age 28. Not coincidentally, that’s also the average age we get married.

Marrying your best friend is enough of a cultural expectation that if I admit I didn’t, people might pity me. But here’s the secret: I’m actually the lucky one. I have a husband who isn’t my best friend. And I have a best friend whom I’m not married to. They play different roles in my life, and I need them both.

One Person Can’t Meet All Your Needs

For Christians, marriage is a relationship set apart, wherein we assume the cares and concerns of our spouse (1 Cor. 7:32–35; Eph. 5:22–33) in a way that supersedes any other friendship. Of course married people find their most significant relationship in their husband or wife—but that doesn’t equate to being BFFs.

I worry that the saying “I married my best friend” conflates the two types of relationships, distorting our views of both.

My marriage remains my priority... But without my friends, my relationship with my husband—and with God—would suffer.

Researchers have already noticed the trend: People increasingly expect their husbands or wives to meet all their social and emotional needs. The phrase implies that, since married people have each other, they don’t have best friends anymore and don’t need them. And it exaggerates the risks young couples already face: setting up unhealthy expectations, looking to each other as the sole source of fulfillment. It also relegates best friends to the realm of singleness.

Making friends in your late 20s and beyond is a whole different game. Not only are there fewer opportunities to meet people, there are also fewer people to meet, since married folks tend to pull themselves off the friendship market. Plenty of young couples dedicate more time to catching up on their Netflix queue than seeing their neighbors, coworkers, and old buddies. My husband and I have been guilty, and so have plenty of our friends. They update Facebook about spending yet another weekend in, joking about becoming “a boring old married couple.”

And yet friends can actually support—not detract from—our marriages. Psychology journalist Carlin Flora writes in her book Friendfluence:

Putting your best self forward for new friends allows you to shine and to see your partner through new eyes as she shines, too. Maintaining older mutual friendships also strengthens the bond between long-term partners: Having people around who think of the two of you as a unit, who admire your relationship, and who expect you to stay together can sustain you through times of doubt or distance.

 

When I got married, I knew I didn’t want us to become one of those couples who stopped making friends or fell out of touch. Maybe it’s because I knew I couldn’t rely on my husband, who is in the Army, to always be there to meet my needs. Or maybe it’s because I have really incredible friends, whom I’d much rather see Twilight with or ask fashion advice from than my spouse.

Don’t get me wrong: My marriage remains my priority, the place where God has done the most to reveal the gospel to me. But without my friends, my relationship with my husband—and with God—would suffer. I gain much from being around others and receiving their perspectives and their prayers. Time spent with friends also keeps me from idolizing my husband as “my everything,” a habit many married people struggle to resist.

Making Friendship a Priority

I want to intentionally be open to the multiple relationships God will use to work in my life and the many opportunities I may have in others’. But those kinds of relationships don’t happen by accident. Here’s where friendship is like marriage: It takes work.

On her sitcom The Mindy Project, Mindy Kaling declares, “A best friend isn’t a person. It’s a tier.” I’m in her camp. I have a best friend from growing up, a best friend from college, and others from my early 20s. It’d be easy for these relationships to fizzle out, so I make it a priority to visit, even when it requires sacrifice, and to regularly text, call, and write in between.

We moved around a lot when I was growing up. Always the new girl in school, I think back to a note my mom placed in my lunchbox: “To make a friend, you have to be a friend.” Decades later, I’ve found it still takes initiative and effort to sustain friendships. If we look to Jesus as an example, he selected friends to invest in. He had a best friend (John) and a best friend tier (the disciples). He says to them in John 15:12–15 (ESV):

This is my commandment, that you love one another as I have loved you. Greater love has no one than this, that someone lay down his life for his friends. You are my friends if you do what I command you. No longer do I call you servants, for the servant does not know what his master is doing; but I have called you friends, for all that I have heard from my Father I have made known to you.

Verse after Bible verse speaks of the “sweetness” (Prov. 27:9, ESV) and value of faithful friends. God wouldn’t have us give up these relationships for marriage, but continue to sharpen (Prov. 27:17) and grow one another in this special context.

We regularly talk about upholding and enhancing marriage and family life for their gospel witness, as we should. I’d like us to start doing the same with friendship. We need friends not only for our health, careers, and happiness, but more importantly, for the way they witness to our siblinghood in Christ. And from the meaningful ties of friendship often come opportunities to introduce others to Jesus, the one who calls us his friends in the first place (John 15:15).

I didn’t marry my best friend. Instead, I married my husband, with all my best friends beside me to celebrate. It was the happiest day of my life. I got—and still get—to have both.

Kate Shellnutt is associate editor of Her.meneutics, CT’s women’s site.

 
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I Didn’t Marry My Best Friend
Posted by: Dr. Dan L. Boen AT 02:23 pm   |  Permalink   |  Email
Tuesday, July 08 2014

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The following article is located at: http://www.christianitytoday.com/le/2014/july/can-neuroscience-help-us-disciple-anyone.html

Can Neuroscience Help Us Disciple Anyone?

Can Neuroscience Help Us Disciple Anyone?

Brain science and the renewal of your mind.

For an article about ministry and neuroscience, it seems only right to begin with Scripture. So we start with one of the great neurological texts of the Bible: "David put his hand in his bag, and took thence a stone, and slang it, and smote the Philistine in his forehead, that the stone sunk into his forehead; and he fell upon his face to the earth" (1 Sam. 17:49, KJV).

Neuroscience has gained so much attention recently that it can seem like we're the first humans to discover a connection between the physical brain and spiritual development. But way back in Bible times, before EEGs and HMOs, people had noticed that putting a rock through someone's skull tends to inhibit their thinking.

For those of us in church leadership, information about "the neuroscience of everything" is everywhere. How much do we need to know about it? What new light does it shed on human change processes that those of us in the "transformation business" need to know? Does it cast doubt on the Christian view of persons as spiritual beings who are not merely physical?

Why is Neuroscience Exploding?

Neuroscience studies the nervous system in general and the brain in particular. Neurobiology looks at the chemistry of cells and their interactions; cognitive neuroscience looks at how the brain supports or interacts with psychological processes; something called computational neuroscience builds computer models to test theories.

Most of our behavior-typing, tying a shoe, or driving-is governed by habits imprinted on our brains. So is discipleship.

Because the mind can be directed to any topic, there can be a "neuroscience" of almost any topic. Neurotheology looks at the brain as we believe, think, and pray about God. Researcher Andrew Newberg has shown the brain-altering power of such practices as prayer by looking at changes in the brain-state of nuns engaged in the practice for over 15 years as well as Pentecostals praying in tongues. It turns out that intense practice of prayer means their brains are much more impacted by their prayer than inexperienced or casual pray-ers. To find out who the true prayer-warriors in your church are, you could hook everybody up to electrodes, but it might be a little embarrassing. Paul Bloom pointed out that we shouldn't be surprised by this; the surprising thing would be if people experience a profound state without their brains being affected.

Brain studies made steady progress through the twentieth century; my own original doctoral advisor at Fuller Seminary was Lee Travis, who pioneered the use of the electroencephalogram at the University of Iowa in the 1930s. But for a long time, no one could actually look inside a working brain to watch it in operation.

That changed in the 1990s with functional Magnetic Resonance Imaging (fMRI), which allows researchers to track the flow of oxygen-rich blood (a proxy for neuron activity) in real time. Now it became possible to find out what part of the brain is involved in any given sequence of conscious activity, and how brain functions of liberals versus conservatives or religious versus non-religious people may differ from each other. It also became possible to find out if that guy in the second row whose eyes are closed when you're preaching really does have something going on in his brain during the sermon.

Why I'm Thankful for Neuroscience

"All truth is God's truth," Augustine said, and a deep part of what it means to "exercise dominion" is to learn all we can about what God has created. And there is very little God created that is more fascinating or more relevant to our well-being than our brains.

Neuroscience has immense potential to relieve human suffering. Already neuroscientists have found ways to alleviate symptoms of Parkinsons and create cochlear implants. Our church had a baptism service recently and several of those being baptized were young adults who suffer from cognitive challenges. In each case their parents were in tears. For those of us doing ministry to be aware of advances in brain science is part of caring for those in our congregation.

Research into the teenage brain made clear that the human brain isn't really fully developed until people are well into their twenties. Previously it was thought that the teenage brain was just "an adult brain with fewer miles on it." It turns out that the frontal lobes, which are associated with choosing and decision-making as well as with impulse-control and emotional management, are not fully connected—they lack the myelin coating that allows efficient communication between one part of the brain and another.

Christians have brains and neurons that are as fallible as atheist neurons and new age neurons.

This helps explains the ancient mantra of parents and student ministry leaders everywhere: "What were you thinking?" Churches can help parents of teenagers understand why a practice as simple as insisting their teenage children get a good night's sleep is so necessary. They can also help parents set expectations for their teenagers' emotional lives at an appropriate level. They can also remind church leaders who are doing talks for teenagers to keep them short!

Neuroscience can also teach us compassion. For too long people who suffered from emotional or mental illness have been stigmatized. Churches—which should have been the safest places to offer healing and care—were sometimes among the most judgmental communities because it was assumed that if people simply got their spiritual lives together, their emotions should be fine.

Rick and Kay Warren noted after the death of their son: "Any other organ in my body can get broken and there's no shame, no stigma to it. My liver stops working, my heart stops working, my lungs stop working. Well, I'll just say, 'Hey, I've got diabetes, or a defective pancreas or whatever,' but if my brain is broken, I'm supposed to feel shame. And so a lot of people who should get help don't."

Pastors can offer great help to their congregation when we simply acknowledge the reality that followers of Jesus do not get a free pass from mental health problems. Christians have brains and neurons that are as fallible as atheist neurons and New Age neurons.

Beyond that, I'm thankful for neuroscience because it is helping us understand better how our bodies work, and that enables us better to "offer our bodies a living sacrifice to God." Knees that spend long hours in prayer change their shape. So do brains.

The Limits of Neuroscience

One of the reasons it's important for pastors to be conversant with the topic is that neuroscience is being accorded enormous authority in our day—not always for good reasons. I joke with a neuroresearcher friend of mine (who helped a lot with this article but wants to remain anonymous) that the easiest way to get an article published today is to pick any human behavior and …

  1. Show which parts of the brain are most active when thinking about that topic;
  2. Explain why evolutionary psychology has shown that behavior is important to our survival;
  3. Give four common-sense tips for handling that behavior better—none of which has anything to do with #1 or #2.

Precisely because neuroscience has so much prestige, those of us who teach at churches need to be aware of its limitations as well as its findings. It's one thing to say that our brain chemistry or genetic predisposition may affect our attitudes or beliefs or behaviors. It's another thing to say we are nothing but our brain chemistry.

Sometimes writers make claims in popular literature that would never make it into a peer-reviewed academic journal. One example is a recent book, We Are Our Brains, which makes the claim that there is no such thing as free will, that our brains predetermine everything including our moral character and our religious leanings, so there is no good reason to believe God exists either.

Because neuroscience has so much prestige, we church leaders need to be aware of its limitations as well as its findings.

People may be under the impression that "science" has proven this. This is sometimes called "nothing buttery"; the idea that we are "nothing but" our physical selves.

Yet let's be clear: we are not just our brains.

No one has ever seen a thought, or an idea, or a choice. A neuron firing is not the same thing as a thought, even though they may coincide. A brain is a thing, a human being is a person.

God doesn't have a brain, Dallas Willard used to say, and he's never missed it at all. (Dallas actually used to say that's why for God every decision is a "no-brainer," but I will not repeat that because it's too much of a groaner, even for Dallas.)

Neuroscience can help us understand moral and spiritual development. It shows the importance of genetic predispositions in areas of character and attitudes—from political orientation to sexuality. But it has not shown that personal responsibility or dependence on God are irrelevant. It does not replace the pastor or trump the Bible.

The Neuroscience of Sin And Habits

Neuroscience has shown us in concrete ways a reality of human existence that is crucial for disciples to understand in our struggle with sin. That reality is this: mostly our behavior does not consist of a series of conscious choices. Mostly, our behavior is governed by habit. Most of the time, a change of behavior requires the acquisition of new habits. Willpower and conscious decision have very little power over what we do.

A habit is a relatively permanent pattern of behavior that allows you to navigate life. The capacity for habitual behavior is indispensible. When you first learn how to type or tie a shoe or drive a car, it's hard work. So many little steps to remember. But after you learn, it becomes habitual. That means it is quite literally "in your body" (or "muscle memory"). At the level of your neural pathways. Neurologists call this process where the brain converts a sequence of actions into routine activity "chunking."

Chunking turns out to be one of the most important dynamics in terms of sin and discipleship. Following Jesus is, to a large degree, allowing the Holy Spirit to "re-chunk" my life. This is a physical description of Paul's command to the Romans: " … but be transformed by the renewing of your mind."

Habits are enormously freeing. They are what allows my body to be driving my car while my mind is planning next week's sermon.

But sin gets into our habits. This is the tragedy of fallen human nature. Self-serving words just come out of my mouth; jealousy comes unbidden when I meet someone who leads a larger church or preaches better; chronic ingratitude bubbles up time and again; I cater to someone I perceive to be attractive or important.

Neuroscience research gives us a clearer picture (and deeper fear) of what might be called the "stickiness" of sin. It is helping us to understand more precisely, or at least more biologically, exactly what Paul meant when he talked about sin being "in our members." He was talking about human beings as embodied creatures—sin is in the habitual patterns that govern what our hands do and where our eyes look and words our mouths say. Habits are in our neural pathways. And sin gets in our habits. So sin gets in our neurons.

Like so much else, our neurons are fallen, and can't get up. They need redemption.

The Neuroscience of Discipleship

You can override a habit by willpower for a moment or two. Reach for the Bible. Worship. Pray. Sing. You feel at peace with God for a moment. But then the sinful habit reemerges.

Habits eat willpower for breakfast.

When Paul says there is nothing good in our "sinful nature," he is not talking about a good ghost inside you fighting it out with a bad ghost inside you. Paul is a brilliant student of human life who knows that evil, deceit, arrogance, greed, envy, and racism have become "second nature" to us all.

Sanctification is, among other things, the process by which God uses various means of grace to re-program our neural pathways. This is why Thomas Aquinas devoted over 70 pages of the Summa Theologica to the cultivation of holy habits.

It's why 12-step groups appeal, not to willpower, but to acquiring new habits through which we can receive power from God to do what willpower never could.

Neuroscience has helped to show the error of any "spirituality" that divorces our "spiritual life" from our bodies. For example, it has been shown that the brains of healthy people instructed to think about a sad event actually look a lot like the brains of depressed people.

"Spiritual growth" is not something that happens separate from our bodies and brains; it always includes changes within our bodies. Paul wrote, "I beat my body to make it my slave"—words that sound foreign to us, but in fact describe people who seek to master playing the cello or running a marathon. I seek to make the habits and appetites of my body serve my highest values, rather than me becoming a slave to my habits and appetites. What makes such growth spiritual is when it is done through the power and under the guidance of the Holy Spirit. Paul's language remains unimprovable: We offer our bodies as living sacrifices so that our minds can be renewed.

One of the great needs in churches is for pastors and congregations to experiment with discipleship pathways that address the particular context that we face. Pornography (and misguided sexuality in general) has always rewired the brain. But now porn is so incredibly accessible that men and women can be exposed to it any time they want for as long as they want as privately as they want. Each time that connection between explicit images and sexual gratification is established, the neural pathway between the two grows deeper—like tires making ever-deepening ruts in a road.

Simply hearing that sexual sin is bad, or hearing correct theological information, does not rewire those pathways. What is required is a new set of habits, which will surely include confession and repentance and fellowship and accountability and the reading of Scripture, through which God can create new and deeper pathways that become the new "second nature," the "new creation."

At our church not long ago, one of our members spoke openly about many years of shame around sexual addiction. His courageous openness stilled the congregation, and it led to the formation of a recovery ministry that is one of the most vibrant in our church.

The Neuroscience of Virtue

Kent Dunnington has written a wonderfully helpful book, Addiction and Virtue. He notes that many federal health institutes and professional organizations assume addiction is a "brain disease" purely "because the abuse of drugs leads to changes in the structure and function of the brain." However, playing the cello and studying for a London taxi license and memorizing the Old Testament also lead to changes in the structure and function of the brain. Shall we call them diseases, too?

Dunnington says that addiction is neither simply a physical disease nor a weakness of the will; that to understand it correctly, we need to resurrect an old spiritual category: habit. We have habits because we are embodied creatures; most of our behaviors are not under our conscious control. That's a great gift from God—if we had to concentrate on brushing our teeth or tying our shoes every time we did that, life would be impossible.

But sin has gotten into our habits, into our bodies, including our neurons.

Partly, we may be pre-disposed to this.

For example, people with a version of the Monoamine oxidase A (MOA) gene that creates less of the enzyme tend to have more troubles with anger and impulse control. (If you have that version of MOA, you're feeling a little testy right now.) This means that when Paul says "In your anger, do not sin," some people are predisposed to struggle with this more than others.

That doesn't mean that such people are robots or victims or not responsible for their behavior. It does explain part of why Jesus tells us to "Judge not"; none of us knows the genetic material that any other person is blessed with or battling in any given moment.

This also shows that the people in our churches will not be transformed simply by having more exegetical or theological information poured into them—no matter how correct that information may be. The information has to be embodied, has to become habituated into attitudes, patterns of response, and reflexive action.

The reason that spiritual disciplines are an important part of change is that they honor the physical nature of human life. Information alone doesn't override bad habits. God uses relationships, experiences, and practices to shape and re-shape the character of our lives that gets embedded at the most physical level.

A few decades ago scientists did a series of experiments where monkeys were taught how to pinch food pellets in deep trays. As the monkeys got faster at this practice, the parts of the brain controlling the index finger and thumb actually grew bigger. This and other experiments showed that the brain is not static as had often been thought, but is dynamic, able to change from one shape to another. This is true for human beings as well. The part of violinists' brains that controls their left hand (used for precise fingering movements) will be bigger than the part that controls their right hand.

But wait—there's more. In another study, people were put into one of three groups; one group did nothing; one exercised their pinky finger, a third group spent 15 minutes a day merely thinking about exercising their pinky finger. As expected the exercisers got stronger pinkies. But amazingly—so did the people who merely thought about exercising. Changes in the brain can actually increase physical strength.

No wonder Paul wrote: "Whatever is true, whatever is honorable, whatever is just, whatever is pure, whatever is pleasing, whatever is commendable, if there is anything worthy of praise, think about these things." Every thought we entertain is, in a real sense, doing a tiny bit of brain surgery on us.

Here's a thought worth contemplating: what must Jesus' brain have been like? Imagine having neural circuits honed and trained to trust God, to respond to challenge with peace, or to irritation with love, or to need with confident prayer.

Here's another thought worth contemplating: We have the mind of Christ.

That's worth wrapping your brain around.

John Ortberg is pastor of Menlo Park Presbyterian Church in California.

Posted by: Dr. Dan L. Boen AT 01:40 pm   |  Permalink   |  Email
Thursday, May 08 2014

'Love Addiction': Biology Gone Wrong?

Deborah Brauser

May 07, 2014

NEW YORK ― "Love addiction," a condition characterized by severe pervasive and excessive interest toward a romantic partner, may actually be a form of attachment disorder, new research suggests.

A new literature review of studies using the terms "love addiction," "pathological love," and "behavioral addiction" showed possible involvement of the brain reward dopaminergic system as well as attachment-related biological systems.

"We wondered where does love, a feeling of well-being, devolve into addiction? And what might be the criteria for love addiction and its destructive and dysfunctional behaviors?" asked Vineeth P. John, MD, associate professor of psychiatry and behavioral health at the University of Texas Health Science Center in Houston, during a press briefing here at the American Psychiatric Association 2014 Annual Meeting.

Still, he told Medscape Medical News that it is important not to medicalize normal, albeit deep, love. Instead, clinicians should be concerned if patients stay in a relationship despite danger or if have severe pining long after a breakup despite knowing the relationship is over.

"There is an urgent need for a better conceptualization of [love addiction] from a nosological and neurobiological perspective," the investigators note.

"This would be the first step in devising controlled studies aiming at properly assessing the efficacy of different psychosocial and pharmacological interventions in the treatment of this intriguing condition."

Lack of Control

Dr. John reported that the researchers wanted to question whether being addicted to love was possible and if so, whether it could be a diagnosable disorder.

Dr. Vineeth John

They defined love addiction as a pattern of maladaptive behaviors and intense interest toward 1 or even more romantic partners at the detriment of other interests and resulting in a lack of control and significant impact on functionality.

Although it can occur simultaneously with substance dependence or sex or gambling disorders, it can also be considered an addiction behavior itself, a part of a mood or obsessive-compulsive disorder, or even a part of erotomania.

"It is thought that it affects as many as 3% of the population. And in certain subsets of young adults, it may even go up to 25%," said Dr. John.

He added that individuals who are most at risk for the condition include those with an immature concept of love, a maladaptive social environment, or high levels of impulsivity and anxiety; are anxious-ambivalent or "seductive narcissists"; or have structural affective dependence.

Results from the analysis showed that a picture of a participant's "beloved" elicited activation in the brainstem, the right ventral tegmental area (VTA), and the caudate nucleus regions. These areas have been shown to be central to the brain's reward, memory, and learning functions and have been implicated in substance abuse.

In addition, addiction and attachment disorders share overlapping neural circuits, through the VTA to the nucleus accumbens.

"So basically, what we might be looking at is an attachment problem," he said.

Love Molecules

He also reported that 4 possible "molecules of love" include dopamine (which incites desire and facilitates repetition of love behavior), oxytocin (which mediates social behavior), the opioid hormone (which activates pleasure sensations), and vasopressin (which affects protective behaviors).

Interestingly, men who carried the "allele 334 for the gene coding for vasopressin receptor (AVP R1A)" showed less stable relationships.

"But the most plausible and practical aspect of love addiction would be to look at how to treat it," said Dr. John.

Because they found few studies examining benefits of psychotherapy and no studies assessing the efficacy of medications for this condition, the investigators came up with hypothetical guidelines for target symptom interventions.

For psychosocial treatments, they suggested self-help groups, cognitive-behavioral therapy, psychodynamic psychotherapy, or enrolling in Sex and Love Addicts Anonymous.

In addition, they suggested using selective serotonin reuptake inhibitors and/or antidepressants to treat obsessive thoughts about a romantic partner; mood stabilizers to treat mood instability or seeking out multiple partners; mood stabilizers, antipsychotics, naltrexone, or buprenorphine for treating impulsive seeking of romantic partners; and oxytocin or vasopressin for treating impaired attachments.

"It might be possible to devise drug-based therapies for the treatment of difficult love, based on neurobiological substrates," said Dr. John.

"But this is clearly a futuristic concept. We cannot medicalize noble human emotions. This particular addiction has to be harmful, disruptive, and destructive and cause significant psychological distress. And the treatment has to be totally voluntary," he added.

"Overall, it's time to think about our patients, or at least a small subset of them who are clearly suffering with what is probably an attachment problem."

Worth Pursuing

"I think this is a very important area of study," said Jeffrey Borenstein, MD, president and CEO of the Brain and Behavior Research Foundation in New York City.

Dr. Jeffrey Borenstein

"The issue of attachment is extremely important because it relates to other conditions that we treat, including some of the personality disorders," he added.

Dr. Borenstein, who was not involved with this research, was moderator of the press briefing.

He noted that the investigators' approach of looking specifically at the question of love addiction was interesting.

"Obviously Dr. John is not saying that we have pills for this or even that we should be treating this. But I think it's an area of study worth learning more about," concluded Dr. Borenstein.

The study authors report no relevant financial relationships.

American Psychiatric Association's 2014 Annual Meeting. Abstract NR8-35. Poster presented May 6, 2014.

 
Posted by: Dr. Dan L. Boen AT 09:16 am   |  Permalink   |  Email
Thursday, March 27 2014

Your Brain as a Car

  • Driver sits on the Front left side
    • Thinks
    • Makes Decisions
    • Freewill sits in this sit
    • This part controls the wheel, brakes, and gas
    • The Adult part of the brain
    • Is confused or overwhelmed by stress
    • Stress comes from outside/other drivers
    • Stress comes from inside/other passengers
    • Bottom line Behavior sits in this seat—this is what you do
  • The Navigator sits on the right front side
    • This is your conscience
    • Your moral values and belief system resides here
    • This is your Parent within
    • This part has the map and looks where you have been, where you are, and where you are heading
    • It influences the Driver by telling the Driver what it Believes you should be doing
    • It feels guilty about the past (what you did or did not do)
    • It feels worried or concerned about the present (what you are doing or not doing)
    • It feels anxious about the future (where you are or are not heading)
    • It is in continual dialogue with the Driver while keeping alert and watchful of the other passenger in the backseat
  • The Child sits in the backseat
    • All the primary emotions of anger, fear, and joy reside here
    • Anger, fear, and joy can be combined to make all the other emotions
    • The child sits in front of a surround sound movie screen that has all the memories/movies of the past
    • Movies/memories can be past, present, or future if stored as real
    • The child does not know the difference between real and imagined
    • The child thinks in pictures, images, and emotions but not so much in words
    • The child sees what is going on in the front seat and senses if the two adults in the front are in agreement
    • The child also looks out the window of the car but sees like a child and not an adult
    • The emergency brake—the fight/flight mechanism is in the backseat with the child
    • Therefore the child does not drive the car but can cause it to brake and can hijack the brain
    • The child is not immoral but amoral
    • The child moves towards pleasure and away from pain
    • Memories of pain are stored in twice the chemical quantity as pleasurable memories at the cellular level
    • The child works on Feelings and emotions regardless of whether they are real or not they are real to the child
  • Congruence or harmony is where the Adult, Parent, and Child are in agreement
    • All information comes into and is screened by the amygdala—the part that directs all sensory data throughout the brain
    • The wiring from the amygdala is shorter to the back of the brain—the child, then the front of the brain—the adults
    • Therefore we react before we think and are then left to explain are actions to ourselves and others
    • As a man/person thinks in his heart (his inner child) so is he
    • Out of the heart (the inner child) the mouth speaks
    • In Romans 7:14-28 Paul describes the conflict between the child and the adult parts of the brain
    • In Romans the 8th chapter he describes how we have to learn to walk by the Spirit and not be sight
  • The insula is the GPS or God Positioning System that fires into the gut
    • Our gut level feelings are up to 70% accurate
    • Decisions made in the brain and not the gut are only on the average 25% accurate
    • We need to learn to trust our gut
    • The insula is more active and developed in people who meditate and pray
  • Bottom line: All parts of the brain need to listen to the insula and learn to trust our gut
Posted by: Dr. Dan L. Boen AT 08:51 am   |  Permalink   |  Email
Monday, August 12 2013
August 12, 2013, 2:53 pm

A Glut of Antidepressants

Over the past two decades, the use of antidepressants has skyrocketed. One in 10 Americans now takes an antidepressant medication; among women in their 40s and 50s, the figure is one in four.

Experts have offered numerous reasons. Depression is common, and economic struggles have added to our stress and anxiety. Television ads promote antidepressants, and insurance plans usually cover them, even while limiting talk therapy. But a recent study suggests another explanation: that the condition is being overdiagnosed on a remarkable scale.

The study, published in April in the journal Psychotherapy and Psychosomatics, found that nearly two-thirds of a sample of more than 5,000 patients who had been given a diagnosis of depression within the previous 12 months did not meet the criteria for major depressive episode as described by the psychiatrists’ bible, the Diagnostic and Statistical Manual of Mental Disorders (or D.S.M.).

The study is not the first to find that patients frequently get “false positive” diagnoses for depression. Several earlier review studies have reported that diagnostic accuracy is low in general practice offices, in large part because serious depression is so rare in that setting.

Elderly patients were most likely to be misdiagnosed, the latest study found. Six out of seven patients age 65 and older who had been given a diagnosis of depression did not fit the criteria. More educated patients and those in poor health were less likely to receive an inaccurate diagnosis.

The vast majority of individuals diagnosed with depression, rightly or wrongly, were given medication, said the paper’s lead author, Dr. Ramin Mojtabai, an associate professor at the Johns Hopkins Bloomberg School of Public Health.

Most people stay on the drugs, which can have a variety of side effects, for at least two years. Some take them for a decade or more.

“It’s not only that physicians are prescribing more, the population is demanding more,” Dr. Mojtabai said. “Feelings of sadness, the stresses of daily life and relationship problems can all cause feelings of upset or sadness that may be passing and not last long. But Americans have become more and more willing to use medication to address them.”

By contrast, the Dutch College of General Practitioners last year urged its members to prescribe antidepressants only in severe cases, and instead to offer psychological treatment and other support with daily life. Officials noted that depressive symptoms may be a normal, transient reaction to disappointment or loss.

Ironically, while many patients in the United States are inappropriately diagnosed with depression, many who actually have it suffer without treatment. Dr. Mark Olfson, a professor of clinical psychiatry at Columbia University Medical Center, noted that from the time they develop major depression, it takes Americans eight years on average to seek care.

Diagnosing depression is an inherently subjective task, said Dr. Jeffrey Lieberman, the president of the American Psychiatric Association.

“It would be great if we could do a blood test or a lab test or do an EKG,” Dr. Lieberman said, noting that similar claims of overtreatment have been made about syndromes like attention deficit hyperactivity disorder. “A diagnosis is made by symptoms and history and observation.”

The new study drew 5,639 individuals who had been diagnosed with depression from among a nationally representative sample of over 75,000 adults who took part in the National Survey of Drug Use and Health in 2009 and 2010. The subjects were then interviewed in person with questions based on the D.S.M.-4 criteria.

Only 38.4 percent of the participants met these criteria for depression during the previous year, Dr. Mojtabai said.

It’s possible some of the participants did not appear to be depressed because they had already been successfully treated, said Dr. Jeffrey Cain, the president of the Academy of Family Physicians. Their improved mood may also have colored the way they responded to questions about the past.

“If I’m checking people who are being treated for high blood pressure and taking medication, I would expect it to be better when I’m checking them,” Dr. Cain said.

According to the D.S.M., a diagnosis of major depressive episode is appropriate if the patient has been in a depressed mood and felt no interest in activities for at least two weeks, and also has at least five symptoms that impair functioning almost every day. These include unintentional weight gain or loss, problems sleeping, agitation or slowed reactions noticed by others, fatigue and low energy, feelings of excessive guilt or worthlessness, difficulty concentrating and recurrent thoughts of death.

“We’re not just talking about somebody who’s having a bad day or got into an argument with their spouse,” Dr. Lieberman said. “We’re talking about something that is severe, meaning it’s disabling and distressing and is not transient.”

Many doctors have long prescribed antidepressants soon after the death of a family member, even though the D.S.M. urges clinicians to differentiate between normal grief and pathological bereavement.

One 50-year-old New York City woman said her doctor prescribed an antidepressant a few weeks after her husband died, even though she thought her feelings of shock and sadness were appropriate.

“He told me, ‘You have to function, you have to keep your job, you have a daughter to raise,’ ” said the woman, who asked that her name be withheld because few friends or family members knew she was taking antidepressants.

Most of the study participants were not receiving specialty mental health care, but Dr. Cain pointed out that it was not clear who was making the misdiagnoses: a psychiatrist, non-psychiatrist physician or other provider, like a nurse practitioner.

But while a psychiatrist may spend up to 90 minutes with a patient before making a diagnosis, patients often are more comfortable with their primary care doctors, who rarely have that kind of time.

Dr. Lieberman suggested watchful waiting may be appropriate in some cases, and more integrated forms of health care may soon make it easier to send patients to a mental health provider “down the hall.”

Doctors need to improve their diagnostic skills, Dr. Mojtabai said, and must resist the temptation “to take out the prescription pad and write down an antidepressant and hand it to the patient.”

Posted by: Dr. Dan L. Boen AT 04:04 pm   |  Permalink   |  Email
Wednesday, August 07 2013

This Month’s Expert: Michael Posternak, M.D., on Choosing Antidepressants

By Michael Posternak, M.D.

This Month's Expert: Michael Posternak, M.D., on Choosing AntidepressantsTCR: Dr. Posternak, thank you for agreeing to speak with us and I also want to thank you for having collaborated on a series of research articles that have been extremely useful to clinicians. I’d like to start with your article about factors that we use when we are selecting antidepressants (Zimmerman, Posternak, et. al., Am J Psychiatry 161:1285-1289, July 2004). How did that study come about?

Dr. Posternak: Most psychiatrists pretty much agree that all antidepressants are more or less equally effective. So if you start with that premise and you have 10-15 antidepressants out there, why are you picking one versus another? And what algorithm are we all using? Dr. Zimmerman developed a questionnaire for psychiatrists to fill out immediately after they wrote antidepressant prescriptions. We asked, “What influenced you to choose that medication?”

TCR: And what were your findings?

Dr. Posternak: We found that there were three compelling factors: The first was avoiding specific side effects, the second was the presence of comorbid psychiatric disorders, and the third was the presence of specific clinical symptoms. For example, many people wanted to avoid sexual side effects or weight gain and would choose meds based on this. And if a patient had depression plus panic disorder, for example, we would lean toward the SSRIs. And if someone’s clinical profile included both insomnia and poor appetite, we might choose Remeron (mirtazapine). As you can see, there was nothing terribly earth shattering about any of these findings, but they give us insight into what factors people are actually considering when they prescribe an antidepressant.

TCR: Do you find that there is much research support for the validity of these factors?

Dr. Posternak: No, because there isn’t much research to begin with. For example, if you look for papers on antidepressant efficacy for patients with comorbidity (and comorbidity is the norm rather than the exception) there is almost nothing out there. Most treatment trials assessing depression exclude patients with comorbid disorders or do not assess for them. A prototypical example would be the common practice of avoiding bupropion in patients with depression and significant anxiety. And yet John Rush and colleagues have published three papers showing no difference between Wellbutrin and sertaline in efficacy for anxiety in depressed patients (see, for example, J Clin Psychiatry 2001; 62:776-781).

TCR: You and Dr. Zimmerman have also written about the concept of “remission,” which has become the gold standard for antidepressant trials lately. How do you suggest we decide when a patient has responded well enough to an antidepressant?

Dr. Posternak: I think that is a terrific question. Even from a research standpoint, there is something problematic about using “remission” as the endpoint of a study. The problem is that, both in clinical trials and in our practices, patients start off with different degrees of depression. So let’s say you define your endpoint as a HAM-D score of 7 or less. A patient who starts at a HAM-D of 26 and has a 50% improvement will not meet criteria for remission, but will nonetheless feel much better than when they started the medication. Many patients may not reach the formally-defined point of remission, and may have residual symptoms and yet you and your patient may decide that you are satisfied with that response and you don’t want to keep pushing the dose or switching medications.

TCR: What research instruments would you suggest for use in our practices?

Dr. Posternak: Over the years, I have come to conclude that the CGI (Clinical Global Impression) is a pretty good judge. I ask patients, “Do you think your depression is partially improved or much improved since starting medication?” Usually if they are “much improved,” this corresponds with a greater than 50 percent improvement on the HAM-D, and most of us are not going to switch medications at that point. You might still try to tweak the regimen to help them sleep or improve their energy, but generally we would say that we have found something that seems to be worth sticking to.

TCR: And what are your favorite medication manipulations for tweaking the regiment to enhance response?

Dr. Posternak: The two that I use the most, and that I think are the simplest and most effective are: 1) Ensuring that patients get adequate sleep, and 2) Enhancing energy.

TCR: Tell me a bit about sleep. Why is this so important in resolving depression?

Dr. Posternak: When people don’t sleep it affects many other things like energy, concentration and mood, often leading to irritability. So one of the simplest interventions that I can do for my patients is to help them get a good night’s sleep. Some people are reluctant to take a sleep medicine and if so, I say to them, “This is important for your depressive illness, because if you don’t sleep well the research studies have demonstrated that you are going to be at higher risk for relapse.”

TCR: What are your “go-to” agents for insomnia?

Dr. Posternak: Well I often start with trazodone, because it is safe, it generally doesn’t lead to tolerance, and people like the fact that it has no addictive potential. I usually start at 25 mg because I don’t want them to get turned off from being groggy in the morning. If it doesn’t work at that dose, I will titrate the dose fairly aggressively until they are either sleeping well or they have limiting side effects. You can safely go up to 600 mg, which is an antidepressant dosage.

TCR: What do you do if trazodone doesn’t work?

Dr. Posternak: I like Remeron, but very often this is not an option because people are concerned about weight gain, so then I will move to benzodiazepines.

TCR: What about the non-benzo’s, like Ambien or Sonata?

Dr. Posternak: I rarely go to these next for a very simple reason, which is cost. I generally stick with the generics. I think that they are at least as effective and they are a fraction of the cost. My sense is that the non-benzos are marketed based on their lower risk of dependence or addiction, and yet I find in my clinical practice that people do not get addicted to sleeping pills. It just doesn’t happen, so why should we spend so much money on these other medications? I explain that to patients.

TCR: What benzos do you usually use?

Dr. Posternak: I simply use Valium (diazepam), 5-10 mg.

TCR: Why Valium and not Ativan (lorazepam) or Restoril (temazepam), or the others?

Dr. Posternak: Lorazepam is short-acting, so I find it less effective. Xanax (alprazolam) is the same thing; it is a very short-acting medication. It may help them fall asleep. It may even help the first few nights, but I find if I am treating more long-term insomnia that tolerance builds up. Restoril should be as effective as Valium in theory based on half-life, but in clinical practice I haven’t found that to be the case.

TCR: What about Klonopin?

Dr. Posternak: Klonopin I find is less sedating, which is useful for a daytime anxiolytic but I find that it is just not as effective as a hypnotic.

TCR: You also mentioned enhancing energy?

Dr. Posternak: Yes, and what I use for this, and what I feel is underutilized, is psychostimulants. A lot of times people are depressed, are not as happy as they would like, because they are not as focused or their energy isn’t as good. Like sleeping pills, stimulants have an immediate effect, which is nice and it is quite dramatic.

TCR: And then which specific medication do you like to use?

Dr. Posternak: Well, being boring and simple, I start with plain old generic Ritalin (methylphenidate) and I dose it 5 to 10 mg twice a day, early morning and early afternoon.

TCR: And what do you tell patients when you give it to them about potential side effects?

Dr. Posternak: I tell them that it is very well-tolerated, that its purpose is to increase their energy and help their concentration, and that we can increase the dose if it doesn’t work. As far as side effects, I’ll say, “You might get a tremor, it could increase your anxiety, it could cause insomnia, it could increase your heart rate, but in general people tolerate it very well.”

TCR: Do you see problems with stimulant abuse?

Dr. Posternak: A small minority of my patients report that they tended to get euphoric on stimulants and then crash afterwards. But this is rare.

TCR: How do you deal with prescribing stimulants long term?

Dr. Posternak: Once they are stable and I want to see them every three months I give them two post-dated prescriptions.

TCR: Is there anything else that you have been doing lately for antidepressant augmentation?

Dr. Posternak: Yes, we just completed a randomized trial of T3 (triidothyronine, trade name “Cytomel”) augmentation, and we found that it accelerated antidepressant response in comparison to placebo augmentation.

TCR: What dose did you use?

Dr. Posternak: 25 mcg QD.

TCR: Many psychiatrists are tempted to use Cytomel but are concerned about causing medical problems by adding thyroid hormone to our patients’ systems. What are your thoughts about that?

Dr. Posternak: I don’t think that they have to be concerned about that. If someone has an arrhythmia, I wouldn’t use it, but otherwise 25 mcg. is a very low dose; it is quite safe and you really don’t have to be concerned about that from a clinical standpoint.

TCR: And before you start, do you recommend that we get any particular labs?

Dr. Posternak: No, it is not necessary. If you use T3 and it works, then you will want to get a TSH at some point just to make sure you are not affecting the thyroid gland. But if it doesn’t work, you’ll just stop the medication and you’ll save your patient a blood draw.

This article originally appeared in:
The Carlat Psychiatry Report
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This article was published in print 1/2006 in Volume:Issue 4:1.

APA Reference
The Carlat Psychiatry Report. (2013). This Month’s Expert: Michael Posternak, M.D., on Choosing Antidepressants. Psych Central. Retrieved on August 7, 2013, from http://pro.psychcentral.com/2013/this-months-expert-michael-posternak-m-d-on-choosing-antidepressants/002640.html


Last reviewed: By John M. Grohol, Psy.D. on 30 Jul 2013
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Monday, July 15 2013

PsyBlog - People Are Happier When They Do The Right Thing

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People Are Happier When They Do The Right Thing

Posted: 15 Jul 2013 06:28 AM PDT

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Communities that pull together in a crisis are happier.

What has happened to people's happiness all around the world as they've faced the economic crisis? How have they coped with job losses, less money coming in, the sense of despair and lack of control over a nightmare that seems to have no end?

That's the question that Helliwell et al. (2013) ask in a new paper in the Journal of Happiness Studies.

They guessed that one answer is one of the oldest in human civilisation: by pulling together.

Pulling together, though, has a new fancy name: social capital. Here are the kinds of things which tell you whether a group of people have 'social capital':

  • How many people do volunteer work in the community?
  • How many people have done a favour for a neighbour in the last month?
  • How many people have given a little money to charity (about $25)?
  • How many people regularly have meals together as a family?

These go on and on, but you get the general idea. It's essentially doing nice things for other people around you; they don't have to be that dramatic like donating a liver, just little boyscout-type activities count.

They then looked at a huge amount of data on both social capital and happiness across 255 metropolitan areas in the US and drew this conclusion:

"...communities with greater social engagement are happier than otherwise equivalent communities and that life evaluations fell by less, in response to unemployment increases, in those communities with high levels of a broad measure of social engagement."

So social capital has a protective effect: by pulling together through doing little things for each other, people helped keep their spirits up during the economic crisis.

Happy countries

Helliwell et al. (2013) also found the same when they compared between countries, not just between US metropolitan areas. They divided countries into those which had become happier since the crisis, those which remained about the same and those that had become less happy.

In the group of countries with falling levels of happiness (which includes the US but not the UK):

"We saw that average happiness drops were far greater than could be explained by their lower levels of GDP per capita, suggesting that social capital and other key supports for happiness were damaged during the crisis and its aftermath."

In contrast, South Korea is a country whose average levels of happiness have rocketed up since the economic crisis. This is partly because the economy has recovered remarkably well, but maybe also because of policies that have encouraged social capital. Here's the President of South Korea explaining:

"Korea has already proposed a new way forward from the global crisis. [...] We decided to share the burden. Employees chose to sacrifice a cut in their own salaries and companies accepted to take cuts in their own profits because they wanted to save their employees and co-workers from losing their jobs."

More than social: pro-social

The explanation for these effects is that humans are fundamentally pro-social so:

"...they get happiness not just from doing things with others, but from doing things both with and for others. Despite a wealth of findings that those who do things for others gain a bigger happiness boost than do the recipients of generosity, people underestimate the happiness gains from unselfish acts done with and for others"

Image credit: Shena Pamella

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